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Oral. cialis is available in coated tablets 2.5, 5, 10 and 20 mg.
- use in adult men :
. In general, the recommended dose is 10 mg taken prior to anticipated sexual activity during or between meals.
Among patients for whom a dose of 10 mg of tadalafil does not produce adequate effect, 20mg might be tried. cialis may be taken at least 30 minutes before sexual activity.
. The maximum dose frequency is once per day.
. Tadalafil 10 mg and tadalafil 20 mg are given in anticipation of intercourse, but they are not recommended for daily use.
. In responding patients to demand treatment that provide frequent use of cialis (at least twice a week), taking one tablet per day, with lower doses of cialis may be considered adequate, the decision depending on the choice of the patient and the doctor's advice.
. In these patients, the recommended dose is 5 mg once daily, at approximately the same time of day. The dose may be reduced to 2.5 mg once daily, depending on individual tolerance.
. The choice of the daily dose should be reassessed periodically.

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- Use in elderly men :
No dosage adjustment is necessary in older men.
- Use in men with renal failure :
No dosage adjustment is necessary in patients with mild to moderate.
In patients with severe renal impairment, the maximum recommended dose is 10 mg.
In patients with severe renal insufficiency, daily administration of tadalafil is not recommended (see sections warnings and precautions and pharmacokinetics).
- Use in men with liver failure :
The recommended dose is 10 mg taken prior to anticipated sexual activity, with or without food.
In patients with severe hepatic insufficiency (Child-Pugh class C), the clinical safety data are limited, therefore, when prescribing cialis, a careful individual assessment of risk / benefit ratio must be made by the prescriber.
In patients with liver failure, no data are available on the administration of doses above 10 mg tadalafil. The daily administration has not been evaluated in patients with hepatic impairment, therefore, the physician should conduct a careful individual assessment of risk / benefit ratio of the prescription (see Pharmacokinetics section).
- Use in men with diabetes : No dosage adjustment is necessary in patients with diabetes. - Use in children and adolescents : cialis is not indicated for patients aged under 18 years.

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